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Updated: Jun 6, 2026
07:05
Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Hailey-Hailey disease treatment with Botulinum toxin type A
Giancarlo Rezende Bessa1, Thaís Corsetti Grazziotin, Ana Paula Manzoni
1Universidade Federal de Ciências da Saúde de Porto Alegre, RS, Brasil.
Anais Brasileiros De Dermatologia
|December 15, 2010
Summary
Botulinum toxin type A injections effectively treated recurrent lesions in the axillae and groin, offering an alternative to traditional therapies. Further research is needed to confirm efficacy and cost-effectiveness due to high treatment costs.
Area of Science:
- Dermatology
- Toxicology
Background:
- Recurrent skin lesions in axillae and groin often present treatment challenges.
- Limited response to conventional therapies necessitates exploring novel therapeutic options.
Observation:
- Two sisters with recurrent lesions unresponsive to standard treatments were administered botulinum toxin type A injections.
- Lesions were located in the axillae and groin areas.
Findings:
- Botulinum toxin type A injections led to complete remission of axillary lesions.
- Marked improvement was observed in groin lesions following botulinum toxin type A treatment.
- The use of systemic antibiotics and topical corticosteroids was avoided.
Implications:
- Botulinum toxin type A shows promise as a treatment for recalcitrant skin lesions in sensitive areas.
- High cost remains a barrier, requiring further investigation into cost-benefit analysis.
- Larger studies are essential to validate the efficacy and cost-effectiveness of this therapeutic approach.
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