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An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
Published on: December 17, 2018
A novel single-labeled fluorescent oligonucleotide probe for mercury(II) ion detection: using the inherent quenching
Lei Wang1, Jingqi Tian, Hailong Li
1State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China.
Journal of Fluorescence
|December 15, 2010
Abstract:
A novel single-labeled fluorescent oligonucleotide (OND) probe for the detection of nanomolar mercury(II) ion in aqueous solution is developed based on the inherent quenching of deoxyguanosines. The formation of hairpin structure of OND-Hg(2+) complex brings deoxyguanosines close to dye, resulting in decreased dye fluorescence due to photoinduced electron transfer from dye to deoxyguanosines.
