Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postoperative Pain Trajectories and Pain Chronification-an Empirical Typology of Pain Patients.

Pain medicine (Malden, Mass.)·2018
Same author

Cage deviation in the subaxial cervical spine in relation to implant position in the sagittal plane.

Neurosurgical review·2017
Same author

[Circadian rule and activity periodicity in the genus carabus].

Oecologia·2017
Same author

[The diurnal activity of carabid beetles].

Oecologia·2017
Same author

Retrospective Matched-Pair Cohort Study on Effect of Bisegmental Fenestration versus Hemilaminectomy for Bisegmental Spinal Canal Stenosis at L3-L4 and L4-L5.

Journal of neurological surgery. Part A, Central European neurosurgery·2017
Same author

How Many Cases of Spine Surgery Are Performed in Germany? Method of Counting the Number of Cases of Spine Surgery in Germany.

Journal of neurological surgery. Part A, Central European neurosurgery·2016

Related Experiment Video

Updated: Jun 6, 2026

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
07:06

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

Published on: October 10, 2025

[Cervical arthroplasty using the Bryan Cervical Disc System].

Friedrich Weber1, Michael Detzner

  • 1Neurochirurgische Klinik, Kliniken der Stadt Köln gGmbH, Köln, Germany. weberf@kliniken-koeln.de

Operative Orthopadie Und Traumatologie
|December 15, 2010
PubMed
Summary

This study evaluates the Bryan Cervical Disc Prosthesis for treating cervical spine conditions. Results show its effectiveness in managing radicular and myelopathic symptoms, offering a viable surgical option.

Related Experiment Videos

Last Updated: Jun 6, 2026

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
07:06

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

Published on: October 10, 2025

Area of Science:

  • Spine surgery
  • Orthopedic implants
  • Cervical spine disorders

Context:

  • Radicular or myelopathic symptoms affecting the C2-Th1 vertebral segments.
  • Indications include discogenic/spondylotic radiculopathy, acute myelopathy, and neurological deficits.
  • Contraindications involve chronic myelopathy, infection, tumors, OPLL, and certain bone diseases.

Purpose:

  • To assess the efficacy and outcomes of the Bryan Cervical Disc Prosthesis for specific cervical spine pathologies.
  • To evaluate the surgical technique, postoperative management, and clinical results of this artificial disc replacement.

Summary:

  • The Bryan Cervical Disc Prosthesis was implanted in 178 patients, with 92 completing follow-up ranging from 6 to 44 months.
  • Surgical technique involved anterior diskectomy, decompression, and prosthesis insertion after endplate preparation.
  • Radiological and clinical evaluations included range of motion, heterotopic ossification, Oswestry Neck Disability Index, and neurostatus.

Impact:

  • Provides a surgical solution for debilitating cervical spine conditions unresponsive to conservative care.
  • Contributes data on the long-term outcomes and safety of artificial cervical disc replacement.
  • Informs clinical decision-making for surgeons treating cervical radiculopathy and myelopathy.