Related Experiment Video
Updated: Jun 6, 2026

07:06
Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
Published on: October 10, 2025
[Total cervical disk replacement--implant-specific approaches: keel implant (Prodisc-C intervertebral disk
Andreas Korge1, Christoph J Siepe, Franziska Heider
1Wirbelsäulenzentrum, Schön Klinik München Harlaching, München, Germany. akorge@schoen-kliniken.de
Operative Orthopadie Und Traumatologie
|December 15, 2010
Summary
This study demonstrates that the Prodisc-C artificial cervical disc provides dynamic intervertebral support, significantly improving patient outcomes and spinal mobility after surgery for symptomatic cervical disk disease.
Area of Science:
- Orthopedic Surgery
- Neurosurgery
- Spinal Surgery
Background:
- Symptomatic cervical disk disease (SCDD) often necessitates surgical intervention to alleviate spinal canal narrowing.
- Dynamic intervertebral support aims to restore spinal function while minimizing fusion complications.
Purpose of the Study:
- To evaluate the efficacy and safety of a modular artificial cervical disc prosthesis with end-plate fixation.
- To assess clinical and radiologic outcomes following anterolateral implantation for SCDD.
Main Methods:
- A minimally invasive anterolateral approach was used for implantation of 100 Prodisc-C prostheses in 78 patients.
- Surgical technique involved diskectomy, decompression, and prosthesis implantation with central keel fixation.
- Patients underwent 24-month clinical and radiologic follow-up.
Main Results:
- Significant improvements were observed in visual analog scale and Neck Disability Index scores.
- Radiologic assessment revealed enhanced segmental lordosis and mobility in the index segment.
- A low incidence of spontaneous fusion (8.75%) was noted, with no significant impact on clinical outcomes.
Conclusions:
- The Prodisc-C prosthesis offers effective dynamic intervertebral support for the cervical spine.
- The anterolateral approach with keel fixation is a viable surgical option for SCDD.
- The procedure leads to significant functional and radiologic improvements with minimal fusion rates.
Related Concept Videos
Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...