End-tidal CO2 measurement in the detection of esophageal intubation during cardiac arrest

Measurement of end-tidal carbon dioxide (ETCO2) has been used to detect accidental esophageal tube placement in noncardiac arrest situations. The purpose of our study was to determine whether ETCO2 measurement could distinguish tracheal from esophageal tube placement during closed-chest massage (CCM). Twelve large dogs were anesthetized, and endotracheal tubes were placed in both the trachea and the esophagus. Placement was verified by fiberoptic endoscopy. Ventricular fibrillation was induced by a 60-Hz discharge through a right ventricular pacemaker. After four minutes of cardiac arrest, CCM was initiated and continued for 20 minutes. The dogs were divided into two groups: Group A was ventilated through the tracheal tube, and group B was ventilated through the esophageal tube. Unused tubes were removed. ETCO2 was recorded continuously beginning two minutes before arrest until the end of the experiment. There were no significant between-group differences in mean arterial pressure, weight, blood loss, IV fluid volume administered, or prearrest arterial blood gases. ETCO2 differed significantly between the two groups throughout CCM (P = .001). In group A, ETCO2 ranged from 13 to 34 mm Hg (median, 20 mm Hg). In group B, ETCO2 ranged from 2 to 11 mm Hg (median, 3 mm Hg). In this experimental model, measurement of ETCO2 reliably distinguished esophageal from tracheal intubation during cardiac arrest and CCM. If confirmed in human beings, this may prove to be a quick, reliable method of detecting esophageal intubation during cardiac arrest.