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Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery
07:28

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Published on: February 3, 2026

Update on emergency contraception.

Paul M Fine1

  • 1Obstetrics & Gynecology, Baylor College of Medicine, Houston, TX, USA. paul.fine@ppgulfcoast.org

Advances in Therapy
|December 15, 2010
PubMed
Summary
This summary is machine-generated.

Ulipristal acetate is a more effective emergency contraceptive than levonorgestrel, reducing pregnancy risk by 42% up to 72 hours. This new option provides greater pregnancy prevention, even when used beyond 72 hours.

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Last Updated: Jun 6, 2026

Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery
07:28

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Published on: February 3, 2026

Area of Science:

  • Reproductive Health
  • Pharmacology
  • Contraception

Background:

  • Emergency contraception (EC) is crucial for preventing unintended pregnancies.
  • Ulipristal acetate (UPA) is a selective progesterone receptor modulator offering a new EC option.
  • Levonorgestrel (LNG) is an established progesterone-only EC with a 72-hour window.

Purpose of the Study:

  • To compare the efficacy and safety of ulipristal acetate versus levonorgestrel for emergency contraception.
  • To evaluate the effectiveness of UPA up to 5 days post-unprotected intercourse.
  • To assess the pregnancy risk reduction associated with UPA compared to LNG.

Main Methods:

  • Meta-analysis of two randomized clinical trials.
  • Comparison of pregnancy risk between UPA and LNG groups.
  • Assessment of efficacy within the first 72 hours and beyond.

Main Results:

  • Ulipristal acetate demonstrated higher efficacy than levonorgestrel in delaying or inhibiting ovulation.
  • UPA showed a 42% lower pregnancy risk than LNG up to 72 hours post-intercourse.
  • UPA was significantly more effective than LNG in preventing pregnancies when used beyond 72 hours.
  • Side effects for UPA were mild and comparable to LNG.

Conclusions:

  • Ulipristal acetate is a safe and effective emergency contraceptive, superior to levonorgestrel.
  • UPA offers a broader efficacy window (up to 5 days) compared to LNG (72 hours).
  • UPA represents a significant advancement in emergency contraception options.