Microsurgically induced pure arterial aneurysm model in rats.

Area of Science:

• Vascular Surgery
• Surgical Training Models
• Experimental Surgery

Background:

• Developing reliable arterial aneurysm models is crucial for microsurgical training and research.
• Existing models may not accurately replicate human aneurysm dimensions or complexity.
• A need exists for a reproducible model for advanced surgical skill development.

Purpose of the Study:

• To create a reliable and reproducible arterial aneurysm model for microsurgical training.
• To develop a model with dimensions comparable to human aneurysms.
• To facilitate further research into aneurysm development and treatment.

Main Methods:

• Microsurgical creation of arterial aneurysm models at the abdominal aorta bifurcation in Wistar rats.
• Utilized carotid artery grafts for aneurysm construction.
• Employed a cohort of 20 Wistar rats for model development.

Main Results:

• Successful creation of arterial aneurysm models with no reported complications.
• Achieved an average aneurysm model volume of 35.19±5.64 mm³.
• Demonstrated no thrombus formation in the central blood inflow zone.

Conclusions:

• The rat aortic bifurcation arterial aneurysm model is reliable and readily available for microsurgical training.
• The model serves as a valuable platform for scientific studies on arterial aneurysms.
• Facilitates teaching fundamental techniques like suturing and microdissection for vessel repair.