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Related Experiment Video

Updated: Jun 6, 2026

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells
10:33

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Published on: November 18, 2022

Ginseng for cognition.

Jinsong Geng1, Jiancheng Dong, Hengjian Ni

  • 1Evidence-based Medicine Center, Medical School of Nantong University, 19 Qixiu Road, Nantong, Jiangsu, China, 226001.

The Cochrane Database of Systematic Reviews
|December 15, 2010
PubMed
Summary

Ginseng may offer some benefits for cognition, but more high-quality research is needed. Current evidence is limited, particularly for dementia patients, and no serious side effects were reported in healthy individuals.

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Last Updated: Jun 6, 2026

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells
10:33

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells

Published on: November 18, 2022

Area of Science:

  • Herbal Medicine Research
  • Neuroscience
  • Cognitive Science

Background:

  • Ginseng is a widely used herbal medicine with potential effects on the brain and nervous system.
  • Previous studies suggest ginseng may positively impact cognitive performance.

Purpose of the Study:

  • To evaluate the efficacy and safety of ginseng for improving cognitive performance in healthy individuals and those with cognitive impairment or dementia.
  • To assess the quality and quantity of existing research evidence on ginseng's cognitive effects.

Main Methods:

  • Systematic search of multiple databases (Cochrane Dementia and Cognitive Improvement Group, MEDLINE, EMBASE, PsycINFO, CINAHL, LILACS) and clinical trials registries.
  • Inclusion of double-blind, single-blind, randomized, placebo-controlled trials assessing ginseng's effects on cognitive function.
  • Independent data extraction by two reviewers and contact with authors for additional information.

Main Results:

  • Nine randomized controlled trials were identified; five provided extractable data, all involving healthy participants.
  • Analysis suggested potential improvements in some aspects of cognitive function, behavior, and quality of life.
  • No serious adverse events were associated with ginseng use in the included studies.

Conclusions:

  • There is a lack of convincing evidence for Panax ginseng's cognitive-enhancing effects in healthy individuals.
  • High-quality evidence regarding ginseng's efficacy in dementia patients is currently unavailable.
  • Further large-scale, randomized, placebo-controlled trials are necessary to investigate ginseng's effects on cognition across different populations.