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Pancreatic and islet autotransplantation
D C Dafoe1, A Naji, L J Perloff
1Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia.
Hepato-Gastroenterology
|June 1, 1990
Summary
Segmental pancreatic autotransplantation and islet autografting may prevent diabetes post-pancreas resection. However, both techniques carry risks and require further study for long-term efficacy and safety.
Area of Science:
- Endocrinology
- Surgical Oncology
- Transplantation Immunology
Background:
- Pancreatic resection for disease can lead to diabetes.
- Segmental pancreatic autotransplantation and intraportal islet autografting are potential strategies to prevent post-resection diabetes.
- Assessing transplant function typically requires measuring insulin in venous effluent, especially when total pancreatectomy is not performed.