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Correlations between obstetric complications and neurological soft signs in Tunisian patients with schizophrenia

Amel Mrad1, Anwar Mechri, Hela Slama

  • 1Research Laboratory Vulnerability to Psychotic Disorders, Department of Psychiatry, University Hospital of Monastir, Monastir, Tunisia. anwar_mec@yahoo.fr

Psychiatry and Clinical Neurosciences
|December 15, 2010
PubMed

The objective of this study was to examine the correlations between a history of obstetric complications (OC) and neurological soft signs (NSS) in Tunisian patients with schizophrenia. Forty-six patients were assessed using the Krebs et al. NSS scale. History of OC was obtained from the patients' mothers using the McNeil–Sjöström scale. Although there was no significant difference in NSS between patients with and without OC, there were negative correlations between OC total score and motor coordination and integration sub-scores. These negative correlations suggest that OC could enhance the effects of genetic risk factors for schizophrenia.

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