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Outbreak of acute gastroenteritis caused by adenovirus type 41 in a kindergarten

G Gonçalves1, E Gouveia, J R Mesquita

  • 1Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Portugal. aggoncalves@icbas.up.pt

Epidemiology and Infection
|December 16, 2010
PubMed

Insights

An adenovirus 41 outbreak caused gastroenteritis in a Portuguese kindergarten, despite high rotavirus vaccination rates. This highlights the need to include adenoviruses in outbreak investigations.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • An epidemic of gastroenteritis in children prompted an investigation in a Portuguese kindergarten.
  • Gastroenteritis outbreaks in childcare settings require prompt etiological diagnosis and control measures.

Purpose of the Study:

  • To determine the cause of the gastroenteritis outbreak.
  • To assess rotavirus vaccine efficacy, if applicable.
  • To implement necessary control measures.

Main Methods:

  • An epidemiological investigation including interviews and site visits.
  • Collection and laboratory screening of stool samples from affected children.
  • Testing for noroviruses, rotaviruses, and adenoviruses.

Main Results:

  • The overall attack rate was 11.4%, with most cases being mild.
  • High rotavirus vaccination coverage was observed in children under 2 years old.
  • The outbreak was definitively caused by adenovirus 41, not norovirus or rotavirus.

Conclusions:

  • Adenovirus 41 should be considered in the etiological diagnosis of acute gastroenteritis outbreaks in children.
  • Laboratory protocols for gastroenteritis outbreak investigations must include adenovirus testing.

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