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Related Concept Videos

Hypodermis01:02

Hypodermis

The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
Loose Connective Tissue01:26

Loose Connective Tissue

Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
Adipose Tissue
Adipose tissue consists primarily of fat storage cells called adipocytes and little extracellular matrix. A large number of capillaries present within adipose tissue allow rapid mobilization of lipid molecules. White adipose tissue is...

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Related Experiment Video

Updated: Jun 6, 2026

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
09:21

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

Published on: February 18, 2015

Brown adipose tissue in humans.

Kirsi A Virtanen1, Pirjo Nuutila

  • 1Turku PET Centre, University of Turku, Finland.

Current Opinion in Lipidology
|December 16, 2010
PubMed
Summary
This summary is machine-generated.

Human brown adipose tissue (BAT) is active in adults. Recent studies show BAT plasticity and enhanced glucose uptake during cold exposure, highlighting its metabolic importance.

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Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
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Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

Published on: April 1, 2019

Related Experiment Videos

Last Updated: Jun 6, 2026

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
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Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

Published on: February 18, 2015

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
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Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
10:30

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

Published on: April 1, 2019

Area of Science:

  • Metabolic research
  • Adipose tissue biology
  • Human physiology

Background:

  • Human brown adipose tissue (BAT) has been confirmed as functionally active in adults.
  • Recent research indicates ongoing intensive data collection on human BAT.

Purpose of the Study:

  • To review the significance of human brown adipose tissue (BAT) based on recent scientific publications.
  • To explore the plasticity and metabolic activity of BAT in adult humans.

Main Methods:

  • Detection of human BAT using Positron Emission Tomography (PET).
  • Assessment of metabolic activity, including glucose uptake and thermogenesis, under varying temperatures (cold vs. room temperature).

Main Results:

  • Brown adipocytes and myocytes share a common origin, and adipocytes exhibit transdifferentiation capabilities.
  • Cold exposure significantly increases BAT detection probability due to enhanced metabolic activity and thermogenesis.
  • BAT exhibits a 10-15 fold higher glucose uptake rate in cold conditions compared to room temperature.
  • Preliminary findings suggest similarities between BAT and skeletal muscle regarding origin and insulin response.

Conclusions:

  • The adipose organ demonstrates significant plasticity, with brown and white adipocytes interconverting and potentially a 'brite' adipocyte subtype.
  • Human BAT plays a crucial role in thermogenesis and glucose metabolism, particularly under cold conditions.
  • Further research is needed to fully elucidate the hormonal and neuronal regulation of BAT activity and its therapeutic potential.