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Clinical validation of software for a versatile variability analyzer: Assessment of autonomic function.
T S Ananthakrishnan1, G D Jindal, Vineet Sinha
1Electronics Division, Bhabha Atomic Research Centre, Mumbai, India.
Journal of Medical Physics
|December 16, 2010
Summary
This study introduces a new medical analyzer for studying physiological variability, crucial for understanding autonomic nervous system function in disease. The developed software package analyzes data, showing consistent results with expected disease manifestations.
Area of Science:
- Physiological variability research
- Clinical applications of physiological monitoring
Background:
- Extensive research in heart rate variability and blood pressure variability over 40 years.
- Need for simultaneous multi-variability analysis in clinical settings.
Purpose of the Study:
- Introduce a novel medical analyzer for simultaneous physiological variability studies.
- Validate the analyzer and associated software with clinical data.
Main Methods:
- Development of a medical analyzer by Bhabha Atomic Research Centre.
- Data collection from control subjects and diagnosed patients.
- Analysis using a dedicated software package.
Main Results:
- The medical analyzer enables simultaneous study of multiple physiological variabilities.
- Data analysis confirmed consistency with expected autonomic nervous system changes in disease.
- The software package effectively processes complex physiological data.
Conclusions:
- The developed medical analyzer and software offer a valuable tool for physiological variability research.
- Findings support the utility of this system in understanding disease impact on the autonomic nervous system.
- This technology has potential for manifold clinical applications.
