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Effect of pirazolac on prostanoid synthesis by human gastric mucosa in vitro
1Department of Surgery, King's College School of Medicine and Dentistry, Rayne Institute, London, UK.
Drugs Under Experimental and Clinical Research
|January 1, 1990
Abstract:
Pirazolac concentration-relatedly inhibited the accumulation of prostanoids in incubates of human gastric mucosa, but this inhibition was less than that by indomethacin and other commonly used non-steroidal anti-inflammatory drugs. This difference may explain the claim that pirazolac is less damaging to the stomach.