Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

751
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
751
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

1.1K
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
1.1K
Physiology of the Heart: The Cardiac Cycle01:18

Physiology of the Heart: The Cardiac Cycle

9.7K
The cardiac cycle describes the events from one heartbeat to the next. It includes three main phases: diastole, atrial systole, and ventricular systole, all driven by changes in chamber pressures and the function of heart valves.
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
9.7K
Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

Cardiac Output I:Effect of Heart Rate on Cardiac Output

2.7K
Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
2.7K
Anatomy of the Heart01:27

Anatomy of the Heart

120.0K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
120.0K
Dimensional Analysis03:40

Dimensional Analysis

65.0K
Dimensional analysis, also known as the factor label method, is a versatile approach for mathematical operations. The main principle behind this approach is: the units of quantities must be subjected to the same mathematical operations as their associated numbers. This method can be applied to computations ranging from simple unit conversions to more complex and multi-step calculations involving several different quantities and their units.
Conversion Factors and Dimensional Analysis
The unit...
65.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anti-fibrotic effects via regulation of transcription factor Sp1 on hepatic stellate cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology·2012
Same author

M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability.

Proceedings of the National Academy of Sciences of the United States of America·2012
Same author

Biosynthesis of ethyl oleate, a primer pheromone, in the honey bee (Apis mellifera L.).

Insect biochemistry and molecular biology·2012
Same author

Co-delivery strategies based on multifunctional nanocarriers for cancer therapy.

Current drug metabolism·2012
Same author

Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics·2012
Same author

Expression profile analysis of the polygalacturonase-inhibiting protein genes in rice and their responses to phytohormones and fungal infection.

Plant cell reports·2012

Related Experiment Video

Updated: Feb 7, 2026

Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI
06:09

Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI

Published on: July 21, 2023

2.0K

Three-dimensional canine heart model for cardiac elastography.

Hao Chen1, Tomy Varghese

  • 1Department of Medical Physics, The University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

Medical Physics
|December 17, 2010
PubMed
Summary
This summary is machine-generated.

A novel 3D finite element analysis canine heart model aids cardiac function assessment. This model, integrated with ultrasound simulations, accurately evaluates cardiac elastography algorithms for improved diagnostic capabilities.

More Related Videos

A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation
06:57

A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation

Published on: August 5, 2018

9.5K
Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
12:09

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations

Published on: January 8, 2013

14.1K

Related Experiment Videos

Last Updated: Feb 7, 2026

Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI
06:09

Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI

Published on: July 21, 2023

2.0K
A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation
06:57

A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation

Published on: August 5, 2018

9.5K
Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
12:09

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations

Published on: January 8, 2013

14.1K

Area of Science:

  • Biomedical Engineering
  • Computational Biology
  • Medical Imaging

Background:

  • Accurate assessment of cardiac function is crucial for diagnosing heart conditions.
  • Current methods for evaluating cardiac mechanics can be limited in resolution and scope.
  • Developing advanced computational models is essential for improving cardiac imaging techniques.

Purpose of the Study:

  • To introduce a three-dimensional finite element analysis (FEA) based canine heart model.
  • To enable the assessment of cardiac function using this advanced computational model.
  • To evaluate algorithms for cardiac elastography through ultrasound simulations.

Main Methods:

  • A 3D canine heart model was developed based on existing cardiac deformation and motion data.
  • The model was integrated into ultrasound simulation programs to generate synthetic radiofrequency data.
  • A 2D multilevel hybrid method was employed to estimate local displacements and strain from simulated data.

Main Results:

  • Estimated tissue displacements and strains were compared with actual scatterer movement from the canine heart model.
  • The combination of simulation algorithms and the 3D model yielded high-resolution displacement and strain curves.
  • Principal component analysis was applied to parasternal cardiac short axis views for further analysis.

Conclusions:

  • A 3D cardiac deformation model was proposed for validating displacement tracking and strain estimation algorithms in cardiac strain imaging.
  • Ultrasound simulations using the model successfully generated axial and lateral displacement and strain curves.
  • The simulated curves closely matched actual curves, demonstrating the model's utility for evaluating cardiac imaging techniques.