Related Experiment Video
Updated: Jun 6, 2026
07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
A silent nasal mass with ophthalmic presentation
Vanita Sarin1, Baldev Singh, Pawan Prasher
1Dept of Otolaryngology, SGRDIMSR, Vallah, Amritsar. vanitasarin@yahoo.co.in
Orbit (Amsterdam, Netherlands)
|December 17, 2010
Summary
Nasal chondromesenchymal hamartoma (NCMH) is a rare pediatric tumor that can mimic cancer. Early recognition and complete surgical removal are key to successful treatment and avoiding misdiagnosis.
Area of Science:
- Pediatric pathology
- Surgical oncology
- Medical genetics
Background:
- Nasal chondromesenchymal hamartoma (NCMH) is a rare benign tumor in children.
- NCMH can be misdiagnosed due to overlapping features with other soft tissue tumors.
- Accurate diagnosis is crucial to avoid unnecessary or harmful treatments.
Observation:
- A case of NCMH in a 2.5-year-old child is presented.
- Histological examination revealed a mix of mesenchymal elements, including spindle cells, collagen, and osseous/chondroid tissue.
- Immunohistochemistry showed sensitivity to SMA and calponin.
Findings:
- NCMH exhibits benign biological behavior.
- Complete surgical resection is the recommended treatment.
- Histological and immunohistochemical features aid in diagnosis.
Implications:
- Increased awareness of NCMH can improve diagnostic accuracy in pediatric cases.
- Correct diagnosis prevents misclassification as malignant, avoiding aggressive therapies.
- Complete resection ensures favorable outcomes for this benign condition.
Related Concept Videos
01:24Nose and Nasal Cavity
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
01:27Cranial Bones: Lateral View
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
01:30Epistaxis
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:29Suctioning the Nasopharyngeal Airway
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
01:03Olfactory Receptors: Location and Structure
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...