Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Alpha heavy chain disease].

J P Teulières, R Lambert, A Vachon

    La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
    |May 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Prediction of bone anisotropic mechanical properties in osteoporotic human vertebral body from microstructural parameters.

    Computer methods in biomechanics and biomedical engineering·2013
    Same author

    Penicillin in the treatment of lung abscesses.

    Journal de medecine de Lyon·2010
    Same author

    Trinitrin treatment of biliary hypertonia.

    Archives des maladies de l'appareil digestif et des maladies de la nutrition·2010
    Same author

    Trinitrin treatment of billary hypertonia.

    Lyon medical·2010
    Same author

    A case of phytobezoar with pseudo-neoplastic symptoms.

    Lyon medical·2010
    Same author

    [Large granular T-cell lymphocytic leukemia disclosed by bilateral uveitis: association with celiac disease].

    La Revue de medecine interne·1997
    Same journal

    [Dizziness, lipothymia, syncope; symptomatology and therapy].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Antral reaction; its semeiologic value in ulcers of the lesser curvature].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Electrocardiographic and anatomoclinical collation in a case of infarct Tn type].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Are there dissociated forms of hypocorticalism; biogram in chronic adrenal insufficiency].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    Paradoxical blood pressure collapse and sudden death in paroxysmal arterial hypertension linked to adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    Same journal

    Paroxysmal arterial hypertension by adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    See all related articles

    Alpha chain disease, a rare condition, requires prompt diagnosis in young individuals presenting with digestive issues. Early identification through serum immunoelectrophoresis and exploratory laparotomy is crucial for effective management.

    Area of Science:

    • Immunology
    • Gastroenterology
    • Oncology

    Background:

    • Alpha chain disease is a rare disorder with fewer than 80 diagnosed cases.
    • It primarily affects young individuals of Arab or Oriental Jewish descent.
    • Digestive symptoms like chronic diarrhea, abdominal pain, or abdominal tumors can indicate the disease.

    Purpose of the Study:

    • To highlight the importance of considering Alpha chain disease in the differential diagnosis for specific patient populations.
    • To outline the key diagnostic procedures for Alpha chain disease.
    • To emphasize the role of Alpha chain disease as a potential model for experimental carcinoma research.

    Main Methods:

    • Serum immunoelectrophoresis using monospecific anti-IgA antiserum to detect paraproteins.

    Related Experiment Videos

  • Exploratory laparotomy to obtain lymph node and intestinal biopsies for staging and prognosis.

    • Main Results:

    • Serum immunoelectrophoresis successfully identifies the paraprotein in 100% of cases.
    • Exploratory laparotomy is essential for staging, determining prognosis, and guiding treatment through biopsies.

    Conclusions:

    • Alpha chain disease diagnosis should be routine in France for young Arab or Oriental Jewish patients with relevant digestive symptoms.
    • The disease, similar to Burkitt's lymphoma, may serve as a model for experimental carcinoma research.