Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Liver Regeneration01:24

Liver Regeneration

The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
Liver Physiology01:30

Liver Physiology

The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can also...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current interventional options for palliative care for patients with advanced-stage cholangiocarcinoma.

World journal of clinical oncology·2024
Same author

Investigating the link between frailty and outcomes in geriatric patients with isolated rib fractures.

Trauma surgery & acute care open·2024
Same author

Laparoscopic resection of primary retroperitoneal schwannoma: A case report.

World journal of clinical cases·2020
Same author

Spontaneous rupture of hepatic hemangiomas: A review of the literature.

World journal of hepatology·2010

Related Experiment Video

Updated: Jun 6, 2026

Isolation of CD133+ Liver Stem Cells for Clonal Expansion
12:06

Isolation of CD133+ Liver Stem Cells for Clonal Expansion

Published on: October 10, 2011

Liver regeneration, stem cells and beyond.

Marcelo Af Ribeiro1

  • 1Marcelo AF Ribeiro Jr, Department of Surgery, Santo Amaro University, Alameda Gregorio Bogossian Sobrinho, 80/155, Santana de Parnaiba - SP, 06543-385, Brazil.

World Journal of Gastrointestinal Surgery
|December 17, 2010
PubMed
Summary

Liver regeneration research is advancing, focusing on stem cell therapy and artificial organs. This editorial reviews current literature on liver repair mechanisms and future therapeutic strategies.

Keywords:
LiverRegenerationStem cellsTransplant

More Related Videos

Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration
08:14

Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration

Published on: May 20, 2015

The Influence of Liver Resection on Intrahepatic Tumor Growth
07:55

The Influence of Liver Resection on Intrahepatic Tumor Growth

Published on: April 9, 2016

Related Experiment Videos

Last Updated: Jun 6, 2026

Isolation of CD133+ Liver Stem Cells for Clonal Expansion
12:06

Isolation of CD133+ Liver Stem Cells for Clonal Expansion

Published on: October 10, 2011

Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration
08:14

Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration

Published on: May 20, 2015

The Influence of Liver Resection on Intrahepatic Tumor Growth
07:55

The Influence of Liver Resection on Intrahepatic Tumor Growth

Published on: April 9, 2016

Area of Science:

  • Hepatology
  • Regenerative Medicine
  • Biotechnology

Background:

  • The liver possesses remarkable regenerative capabilities.
  • Recent advancements highlight the potential of stem cell therapy for liver repair.
  • Understanding liver regeneration is crucial for developing new therapeutic approaches.

Purpose of the Study:

  • To discuss the liver regenerative process.
  • To explore the role of stem cells in liver repair.
  • To review the potential of artificial tissues and organs for liver regeneration.

Main Methods:

  • Literature review of current research on liver regeneration.
  • Analysis of studies focusing on stem cell therapy for liver diseases.
  • Examination of emerging technologies in artificial liver development.

Main Results:

  • The liver's regenerative capacity is a complex process involving multiple cellular and molecular mechanisms.
  • Stem cells show promise in restoring liver function, but challenges remain.
  • Artificial tissues and organs offer a potential alternative for liver replacement.

Conclusions:

  • Further research into liver regeneration mechanisms is essential.
  • Stem cell-based therapies require further development and clinical validation.
  • Artificial liver technologies are a promising area for future therapeutic interventions.