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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
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Published on: July 3, 2014

Recent advances in breast cancer radiotherapy: Evolution or revolution, or how to decrease cardiac toxicity?

Youlia M Kirova1

  • 1Youlia M Kirova, Radiation Oncology, Institut Curie 26, Rue d'Ulm, 75005 Paris, France.

World Journal of Radiology
|December 17, 2010
PubMed
Summary

Radiation therapy is key for breast cancer, but techniques vary. Modern methods aim to reduce side effects like lung and heart toxicity, improving patient outcomes.

Keywords:
Breast cancerCardiac toxicityChemotherapyEjection fractionHerceptinRadiotherapy

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Area of Science:

  • Oncology
  • Radiotherapy
  • Medical Physics

Background:

  • Radiation therapy plays a crucial role in breast cancer management.
  • Significant variations exist in irradiation strategies and volume definitions across institutions.
  • Evolving techniques aim to minimize toxicity and personalize treatment.

Purpose of the Study:

  • To review the current state of breast cancer radiotherapy.
  • To highlight indications, techniques, and potential toxicities.
  • To discuss advancements in reducing radiation-related side effects.

Main Methods:

  • Comprehensive literature review of breast cancer radiotherapy.
  • Analysis of current treatment protocols and technological advancements.
  • Evaluation of evidence regarding internal mammary chain irradiation and cardiac dose reduction.

Main Results:

  • Lack of consensus on optimal irradiation techniques and volume definitions persists.
  • New protocols focus on decreasing lung and heart toxicity.
  • Careful application of internal mammary chain radiotherapy and high-quality techniques are recommended for cardiac dose reduction.

Conclusions:

  • Breast cancer radiotherapy requires careful consideration of techniques and patient anatomy.
  • Ongoing research and technological innovation are essential for improving treatment efficacy and safety.
  • Standardization of techniques and further investigation into optimal volume definitions are needed.