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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: Jun 6, 2026

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

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Arterial spin labeling in neuroimaging.

Sasitorn Petcharunpaisan1, Joana Ramalho, Mauricio Castillo

  • 1Sasitorn Petcharunpaisan, Division of Neuroradiology, University of North Carolina at Chapel Hill, Room 3326, Old Infirmary Building, Manning Drive, Chapel Hill, NC 27599-7510, United States.

World Journal of Radiology
|December 17, 2010
PubMed
Summary
This summary is machine-generated.

Arterial spin labeling (ASL) is a noninvasive MRI technique for measuring tissue perfusion. Advances enhance its sensitivity and applications, making it valuable for neuroimaging research and clinical practice.

Keywords:
Arterial spin labelingArterial spin labeling at multiple inversion timesContinuous arterial spin labelingPerfusion-based functional magnetic resonance imagingPseudocontinuous arterial spin labelingPulsed arterial spin labelingTerritorial arterial spin labelingVelocity-selective arterial spin labeling

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Area of Science:

  • Magnetic Resonance Imaging
  • Biomedical Engineering
  • Radiology

Background:

  • Arterial spin labeling (ASL) is an intrinsic tracer MRI technique.
  • It measures tissue perfusion noninvasively.
  • ASL offers advantages over other perfusion methods and is clinically available.

Purpose of the Study:

  • To review basic knowledge of ASL perfusion.
  • To discuss emerging ASL techniques.
  • To explore clinical applications of ASL in neuroimaging.

Main Methods:

  • Review of existing literature on ASL.
  • Focus on technical advancements and clinical utility.
  • Synthesis of information on ASL principles and applications.

Main Results:

  • ASL provides quantitative perfusion measurements.
  • Technical improvements have increased ASL sensitivity.
  • ASL has expanding applications in neuroimaging.

Conclusions:

  • ASL is a valuable tool for research and clinical studies.
  • Its noninvasive nature and quantitative capabilities are key advantages.
  • Emerging techniques and applications continue to advance ASL in neuroimaging.