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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
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Coronary angiography in noncompaction with and without neuromuscular disorders

C Stöllberger1, J Finsterer, G Blazek

  • 12nd Medical Department, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030 Vienna, Austria. claudia.stoellberger@chello.at

Irish Journal of Medical Science
|December 17, 2010
PubMed

Insights

Coronary arteriosclerosis is uncommon in patients with left ventricular hypertrabeculation/noncompaction (LVHT). This study found no significant impact of coronary findings on LVHT patient prognosis.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Genetics

Background:

  • Left ventricular hypertrabeculation/noncompaction (LVHT) is a rare congenital heart anomaly.
  • The association between LVHT and coronary artery pathology is not well understood.
  • Understanding this relationship is crucial for patient management and risk stratification.

Purpose of the Study:

  • To determine the prevalence of coronary pathologic findings in LVHT patients.
  • To compare clinical characteristics and prognosis between LVHT patients with and without coronary angiography.
  • To investigate differences in coronary pathology between LVHT patients with and without specific coronary findings.

Main Methods:

  • Retrospective analysis of 113 consecutive LVHT patients diagnosed between 1995-2007.
  • Review of clinical data, including coronary angiography (CA) results.
  • Comparison of clinical features, coronary findings, and mortality between subgroups.

Main Results:

  • Coronary angiography was performed in 52 patients.
  • LVHT patients who underwent CA showed higher rates of exertional dyspnea, angina, hypertension, and larger left ventricles.
  • Coronary arteriosclerosis was found in 8 patients and was associated with right-bundle-branch block; however, mortality rates were similar across groups.

Conclusions:

  • Coronary arteriosclerosis is infrequently associated with LVHT.
  • The presence of coronary arteriosclerosis does not appear to significantly impact the prognosis of LVHT patients.
Abstract

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