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Related Experiment Video

Updated: Jun 6, 2026

Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection
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Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection

Published on: December 30, 2025

Liver tissue sparing resection using a novel planning tool.

Frank Pianka1, Matthias Baumhauer, Daniel Stein

  • 1Department of General, Visceral and Transplant Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany.

Langenbeck'S Archives of Surgery
|December 17, 2010
PubMed
Summary
This summary is machine-generated.

Preoperative liver resection planning using Mint Liver software significantly spares liver parenchyma, reducing resected volume by 11.3%. This novel tool enhances surgical planning, preventing liver failure and improving outcomes in hepatic surgery.

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Area of Science:

  • Hepatobiliary surgery
  • Surgical oncology
  • Medical imaging and informatics

Background:

  • Accurate preoperative assessment of liver function, volume, and anatomy is critical for preventing postoperative liver failure.
  • Optimizing surgical safety and outcomes in hepatic resections relies on precise patient evaluation.
  • Preoperative resection planning offers valuable anatomical and volumetric data for liver tissue sparing.

Purpose of the Study:

  • To evaluate the efficacy of a novel resection planning tool, Mint Liver, in hepatic surgery.
  • To assess the tool's ability to provide accurate anatomical and volumetric data for surgical planning.
  • To determine if preoperative planning can lead to sparing of liver parenchyma during resections.

Main Methods:

  • Thirteen patients undergoing hemihepatectomy were included in the study.
  • Preoperative resection planning was conducted using Mint Liver software, with virtual resections calculated using standard and individual surgeon-defined methods.
  • Intraoperative measurements of resected specimen volume and weight were compared with virtual resection volumes, alongside a 14-day patient follow-up.

Main Results:

  • A significant difference (p = 0.001) was observed between standard and individual virtual resection plans across all 13 cases.
  • Virtual resection planning resulted in an average of 92.8 mL smaller resected volume, sparing 11.3% of liver parenchyma.
  • No patients experienced acute liver failure, and the perioperative mortality rate was 0%.

Conclusions:

  • Mint Liver software provides precise anatomical and volumetric information essential for preoperative hepatic resection planning.
  • Preoperative assessment and planning using this tool can effectively spare liver parenchyma during surgical resections.
  • The software is a valuable addition to patient evaluation, particularly for complex liver surgeries and living donor liver transplantation requiring exact volumetry.