Related Experiment Video

Updated: Jun 6, 2026

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat
11:18

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat

Published on: September 12, 2014

Looking to the future of research in pediatric anxiety disorders

John S March1

  • 1Division of Neurosciences Medicine, Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt Street, Durham, NC 27705, USA. john.march@duke.edu

Depression and Anxiety
|December 17, 2010
PubMed

Insights

Translational developmental neuroscience is revolutionizing pediatric anxiety disorder research, shifting focus toward personalized medicine and early interventions for anxious youth. This evolution promises more effective treatments and better outcomes.

Area of Science:

  • Translational developmental neuroscience
  • Mental illness onset
  • Pediatric anxiety disorders

Background:

  • Emerging neuroscience drives understanding of mental illness onset.
  • Restructuring of academic health science centers impacts research.
  • Shifts in intervention development affect pediatric anxiety disorders.

Purpose of the Study:

  • Outline the future direction of pediatric anxiety disorder research.
  • Analyze the impact of neuroscience and healthcare shifts on the field.
  • Discuss the evolution of treatment and practice over the next decade.

Main Methods:

  • Review of a symposium presentation on pediatric anxiety disorders.
  • Analysis of trends in translational neuroscience and intervention development.
  • Forecasting future research and clinical practice in the field.

Main Results:

  • The field is moving beyond traditional trials towards personalized medicine.
  • Translational neuroscience revolutionizes intervention development.
  • An efficient discovery-to-translation continuum enhances intervention dissemination.

Conclusions:

  • Advances in science and medicine will shape future clinical research.
  • Embracing scientific revolutions is crucial for pediatric anxiety disorder research.
  • Focusing on anxious youth will lead to preemptive and curative interventions.
Abstract

More Related Videos

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety04:20

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Published on: November 11, 2022

Related Concept Videos

Anxiety: Overview01:18

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Social Anxiety Disorder01:28

Social Anxiety Disorder

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
Behavior Therapy01:22

Behavior Therapy

Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Theoretical Approaches to Psychological Disorder01:29

Theoretical Approaches to Psychological Disorder

The development of psychological disorders, which are characterized by deviant, maladaptive, and personally distressing behaviors, has been explored through several theoretical approaches.
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...