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Updated: Jun 5, 2026

An Electroporation Method to Transform Rickettsia spp. with a Fluorescent Protein-Expressing Shuttle Vector in Tick Cell Lines
Published on: October 11, 2022
Haemophagocytic syndrome and rickettsial diseases
Antonio Cascio1,2, Salvatore Giordano3, Piera Dones3
1AILMI (Associazione Italiana per la Lotta contro le Malattie infettive) Universit� di Messina, Messina, Italy.
Abstract:
Haemophagocytic lymphohistiocytosis is a rare but potentially fatal disease resulting from dysregulated activation and proliferation of lymphocytes. We present a case of haemophagocytic syndrome occurring in a 5-year-old Italian boy as a complication of Mediterranean spotted fever. The characteristics of this case have been analysed and contextualized among those of another 15 cases of haemophagocytic syndrome associated with rickettsial diseases found through a systematic review of the international literature.
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