Related Experiment Video
Updated: Jun 5, 2026

An In Vitro Model for Studying Cellular Transformation by Kaposi Sarcoma Herpesvirus
Published on: August 25, 2017
Primary Classic Kaposi's Sarcoma of the Penis in an HIV-Negative Patient
Kwang Ho Kim1, Joon Il Choi, Kyoung Ho Ryu
1Department of Urology, Seoul Veterans Hospital, Seoul, Korea.
Abstract:
Kaposi's sarcoma (KS) is a multifocal hemorrhagic sarcoma that occurs primarily on the extremities. KS limited to the penis is rare and a well-recognized manifestation of acquired immune deficiency syndrome (AIDS). However, KS confined to the penis is extraordinary in human immunodeficiency virus (HIV)-negative patients. We present the case of a 68-year-old man with a dark reddish ulcerated nodule on the penile skin, which was reported as a nodular stage of KS. We detected no evidence of immunosuppression or AIDS or systemic involvements in further evaluations. In his past medical history, the patient had undergone three transurethral resections of bladder tumors due to urothelial cell carcinoma since 2000 and total gastrectomy, splenectomy, and adjuvant fluorouracil/cisplatin chemotherapy for 7 months due to advanced gastric carcinoma in 2005. The patient was circumcised and has had no recurrence for 2 years.
Related Concept Videos
Cryptococcal Meningitis
Sexually Transmitted Infections
Genital Herpes
Amebiasis
Retrovirus Life Cycles
Cytomegalovirus Disease

