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A Case of Gardner's Syndrome Associated with Desmoid Tumor

Jimin Chung1, Sun Namkoong, Kyoung Eun Jung

  • 1Department of Dermatology, College of Medicine, Dankook University, Cheonan, Korea.

Annals of Dermatology
|December 18, 2010
PubMed

Keywords:
Desmoid tumorFamilial polyposis coliGardner's syndrome

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Desmosomes

The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...