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Cost-effectiveness model for a specific mixture of prebiotics in The Netherlands
I Lenoir-Wijnkoop1, W M C van Aalderen, G Boehm
1Scientific Affairs, Danone Research, Palaiseau, France.
Using prebiotics in infant formula is a cost-effective strategy for preventing atopic dermatitis in The Netherlands. This approach offers significant health economic benefits, making it a valuable preventive measure.
Area of Science:
- Health Economics
- Pediatric Allergy
- Nutritional Science
Background:
- Atopic dermatitis is a common condition in infants.
- Primary prevention strategies are crucial for managing allergic diseases.
- The role of prebiotics in infant nutrition is an area of active research.
Purpose of the Study:
- To evaluate the cost-effectiveness of using prebiotics for the primary prevention of atopic dermatitis in The Netherlands.
- To estimate the health economic impact of prebiotic supplementation in infant formula.
- To compare prebiotic infant formula with no supplementation.
Main Methods:
- A decision-analytic model was constructed to assess health economic outcomes.
- Data were sourced from published literature, clinical trials, price lists, and national statistics.
- The economic evaluation was conducted from a Dutch perspective in 2009.
Main Results:
- Prebiotic infant formula (IMMUNOFORTIS®) incurred an additional cost of €51 per case.
- This intervention increased Quality Adjusted Life Years (QALYs) by 0.108.
- The incremental cost-effectiveness ratio (ICER) was calculated at €472 per QALY, well below the €20,000/QALY threshold.
Conclusions:
- The use of a specific prebiotic mixture in infant formula demonstrates favorable short- and long-term health economic benefits.
- Prebiotic-supplemented infant formula is a highly cost-effective method for preventing atopic dermatitis in The Netherlands.
- This strategy represents a valuable public health intervention for reducing the burden of atopic dermatitis.
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