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Heterotopic ossification after total hip replacement.

S B Warren1

  • 1Department of Orthopedics, Columbia-Presbyterian Medical Center, New York, New York.

Orthopaedic Review
|July 1, 1990
PubMed
Summary
This summary is machine-generated.

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Heterotopic ossification, or extra bone growth after hip replacement surgery, affects many patients. This condition can cause pain and limit motion, but effective preventive and treatment options exist.

Area of Science:

  • Orthopedic Surgery
  • Bone Biology
  • Medical Imaging

Background:

  • Heterotopic ossification (HO) is common after total hip arthroplasty (THA), occurring in up to 70% of patients.
  • The ectopic bone formed is histologically similar to mature skeletal bone.
  • HO can lead to significant postoperative complications, including limited motion and pain in 2% to 4% of patients.

Purpose of the Study:

  • To review the classification, risk factors, and management strategies for heterotopic ossification following total hip arthroplasty.
  • To highlight effective prophylactic and therapeutic interventions for HO.

Main Methods:

  • Radiographic classification and grading of ossification.
  • Identification of high-risk patient demographics.
  • Review of prophylactic treatments (Indocin, low-dose irradiation).

Related Experiment Videos

  • Evaluation of treatment for established bony bridges (excision and irradiation).
  • Main Results:

    • Males with bilateral hypertrophic osteoarthritis and prior hip surgery are identified as high-risk individuals.
    • Prophylaxis with Indocin or low-dose irradiation is effective in preventing HO.
    • Established bony bridges can be treated with excision and irradiation therapy.

    Conclusions:

    • Heterotopic ossification is a frequent complication of total hip arthroplasty with potential for significant morbidity.
    • Risk stratification and targeted prophylaxis are crucial for managing HO.
    • Current treatment modalities offer effective management for both prevention and established cases of HO.