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Updated: Jun 5, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Community-based co-morbidity of depression and chronic physical illnesses in Hong Kong
Sing Lee1, Yee Ling, Adley Tsang
1The Chinese University of Hong Kong, China. singlee@cuhk.edu.hk
Objective:
To examine the co-morbidity of depression and chronic physical illnesses in a representative sample of Hong Kong Chinese.
Methods:
Five thousand and four participants aged 18-65 years completed a structured telephone interview on major depressive episode (MDE) and eight chronic physical illnesses.
Results:
21.5% (N = 1078) of respondents had any physical illness in the previous 1 year. Twelve-month MDE was found in 15% (N = 162) of these physically ill respondents and was significantly associated with physical illnesses (OR: 2.56, 95% CI: 2.07-3.16, p < 0.001). Number of co-morbid physical illnesses had an incremental association with the risk of MDE.
Conclusion:
Co-morbidity of depression and chronic physical illnesses is common in Hong Kong as in Western countries. This speaks to the need for evidence-based practice that encompasses models of integrated care in Hong Kong.
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