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Updated: Jun 5, 2026

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Published on: May 9, 2021
Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive
Antonio Perino1, Lucia Giovannelli, Rosaria Schillaci
1Dipartimento Materno Infantile, University of Palermo, Palermo, Italy.
Abstract:
A prospective study was performed to assess the relationship between human papillomavirus (HPV) infection in 199 infertile couples and outcome of assisted reproductive technologies (ARTs). A highly statistically significant correlation between pregnancy loss rate (proportion of pregnancies detected by β-hCG that did not progress beyond 20 weeks) and positive HPV DNA testing in the male partner of infertile couples, compared with HPV negatives, was observed (66.7% vs. 15%).
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