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Published on: December 16, 2022
Executive dysfunction associated with stroke in the posterior cerebral artery territory
Key-Chung Park1, Sung-Sang Yoon, Hak-Young Rhee
1Department of Neurology, Kyung Hee Medical Center, School of Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemoon-ku, Seoul 130 702, Korea. kcpark67@medimail.co.kr
Summary
Posterior cerebral artery infarction (PCAI) can cause cognitive decline. Extensive PCAI lesions, particularly those involving the splenium or ventral temporal lobes, lead to broader neuropsychological deficits than isolated occipital lobe injuries.
Area of Science:
- Neuroscience
- Neurology
- Cognitive Psychology
Background:
- Posterior cerebral artery infarction (PCAI) can lead to cognitive decline.
- Lesions in the occipital lobe, especially extending to the parahippocampus or splenium, are linked to cognitive impairment.
Purpose of the Study:
- To investigate patterns of neuropsychological deficits following PCAI.
- To differentiate cognitive impairments associated with isolated occipital lobe lesions versus extensive lesions involving additional brain regions.
Main Methods:
- Studied 12 patients (11 with PCAI, 1 with occipital hemorrhage).
- Classified lesions as isolated occipital lobe or extensive (including splenium/posterior ventral temporal lobes).
- Administered a standardized battery of neuropsychological tests.
Main Results:
- Patients with extensive lesions showed deficits in memory, visuospatial function, executive function, and language.
- Patients with isolated occipital lesions primarily exhibited memory impairment.
- PCAI is frequently associated with executive dysfunction.
Conclusions:
- Extensive PCAI lesions result in more diverse cognitive impairments than isolated occipital lobe injuries.
- PCAI frequently leads to executive dysfunction, highlighting the importance of assessing this cognitive domain.
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