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Updated: Jun 5, 2026

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
Published on: February 21, 2015
Visualization of sequence and structural features of genomes and chromosome fragments. Application to CpG islands,
Juan A Subirana1, Ezequiel Anokian
1Departament d'Enginyeria Quimica, Universitat Politècnica de Catalunya, Av. Diagonal 647, Barcelona, Spain. juan.a.subirana@upc.edu
Abstract:
A very simple new program is presented (G-SQUARES). It is useful in order to visualize the composition and basic structural features of whole genomes and selected chromosome regions. The frequency of all dimer and tetramer sequences is reported. Overall structural features are calculated, such as the tendency for alternation. A direct visual comparison among different sequences is easily available. Furthermore, the features which are visualized indicate further studies which should be carried out. Examples are presented on Alu sequences, CpG islands, whole eukaryotic and bacterial genomes.
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