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Related Concept Videos

X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal crystal...
X-ray Crystallography02:18

X-ray Crystallography

The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
Determination of Crystal Structures01:29

Determination of Crystal Structures

In the late 1800s, the revelation that light extended beyond visible wavelengths led to the discovery of X-rays by Wilhelm Roentgen. Recognized as high-energy electromagnetic radiation with short wavelengths, X-rays prompted exploration into their interaction with crystals. Max von Laue proposed in 1912 that the periodic arrangement of atoms, ions, or molecules in crystals would cause them to diffract X-rays, a hypothesis confirmed through experiments with copper sulfate and zinc sulfide...

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Related Experiment Video

Updated: Jun 5, 2026

On-Chip Crystallization and Large-Scale Serial Diffraction at Room Temperature
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On-Chip Crystallization and Large-Scale Serial Diffraction at Room Temperature

Published on: March 11, 2022

Diffraction structural biology--introductory overview.

Roger Fourme1, John R Helliwell, Jack E Johnson

  • 1Synchrotron SOLEIL, BP 48, Saint Aubin, 91192 Gif sur Yvette, France.

Journal of Synchrotron Radiation
|December 21, 2010
PubMed
Summary
This summary is machine-generated.

This special issue explores diffraction structural biology, showcasing recent advancements in understanding molecular structures. Discover cutting-edge research and techniques revolutionizing the field.

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Microcrystallography of Protein Crystals and In Cellulo Diffraction
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Microcrystallography of Protein Crystals and In Cellulo Diffraction

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Last Updated: Jun 5, 2026

On-Chip Crystallization and Large-Scale Serial Diffraction at Room Temperature
07:42

On-Chip Crystallization and Large-Scale Serial Diffraction at Room Temperature

Published on: March 11, 2022

Microcrystallography of Protein Crystals and In Cellulo Diffraction
09:35

Microcrystallography of Protein Crystals and In Cellulo Diffraction

Published on: July 21, 2017

Area of Science:

  • Structural Biology
  • Biophysics
  • Crystallography

Background:

  • This special issue provides an introduction to diffraction structural biology.
  • It highlights recent advancements and their significance in the field.

Discussion:

  • The collection of papers covers various aspects of diffraction techniques.
  • Emphasis is placed on their application in elucidating complex biological structures.

Key Insights:

  • The issue presents novel findings from diffraction studies.
  • These insights contribute to a deeper understanding of molecular mechanisms.

Outlook:

  • Future directions and potential breakthroughs in diffraction structural biology are discussed.
  • The collection aims to inspire further research and innovation.