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Updated: Jun 5, 2026

An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient
Published on: November 30, 2022
Ventilator-associated pneumonia: role of positioning
Gianluigi Li Bassi1, Antoni Torres
1Pneumology Department, Clinic Institute of Thorax (ICT), Hospital Clinic of Barcelona, Barcelona, Spain.
Avoiding the supine horizontal position is crucial for preventing ventilator-associated pneumonia (VAP). While the semirecumbent position shows benefits, novel body positions are needed to further reduce VAP risks in intubated patients.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Infectious Diseases
Background:
- Ventilator-associated pneumonia (VAP) is a common hospital-acquired infection in intubated patients.
- Body positioning significantly influences VAP pathogenesis, including aspiration and secretion clearance.
- Current strategies focus on head-of-bed elevation and patient positioning.
Purpose of the Study:
- To review the efficacy of supine semirecumbent and prone positions in VAP prevention.
- To highlight the impact of body position on VAP risk factors.
- To explore potential novel body positions for VAP reduction.
Main Methods:
- Systematic review of recent literature on VAP prevention strategies.
- Analysis of studies evaluating semirecumbent, supine, and prone positions.
- Examination of laboratory findings on airway axis and secretion drainage.
Main Results:
- Recent studies question the benefit of semirecumbent position above 30° head elevation.
- Supine horizontal position increases aspiration and VAP risk, especially with enteral feeding.
- Prone position aids secretion drainage but has adverse effects limiting its use.
- Maintaining an endotracheal tube-oropharynx-trachea axis below horizontal is key.
Conclusions:
- Avoidance of the supine horizontal position is recommended to prevent aspiration.
- Routine use of the semirecumbent position is beneficial, though optimal angle requires further study.
- Novel positions like the lateral Trendelenburg may reduce aspiration and improve mucus clearance.
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