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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Active surveillance for localized prostate cancer--current practices and recommendations
Jennifer N Wu1, Marc A Dall'Era
1Department of Urology, University of California, Davis Medical Center, Sacramento, CA, USA. Jennifer.wu@ucdmc.ucdavis.edu
Thescientificworldjournal
|December 21, 2010
Summary
Active surveillance for prostate cancer helps avoid overtreatment of indolent tumors. This approach limits treatment risks and focuses aggressive therapies on men who will benefit most, with favorable early outcomes.
Area of Science:
- Oncology
- Urology
Background:
- Prostate cancer is the most common solid tumor in American men, with high prevalence of small, indolent tumors found in autopsy studies.
- Widespread screening and diagnostic practices raise concerns about prostate cancer overdetection and overtreatment.
Purpose of the Study:
- To evaluate the role of active surveillance in managing low-grade, early prostate cancer.
- To identify tools and strategies for selecting appropriate candidates for active surveillance and managing their follow-up.
Main Methods:
- Review of institutional experiences with active surveillance and delayed selective therapy for early prostate cancer.
- Analysis of data from ongoing clinical trials on watchful waiting and active surveillance.
Main Results:
- Published results from active surveillance programs show favorable outcomes with relatively short median follow-up.
- Data provide insights into patient selection, monitoring, and intervention triggers for active surveillance.
Conclusions:
- Active surveillance offers a strategy to limit treatment-related morbidity in men with indolent prostate cancer.
- Further evidence from clinical trials will refine the management of early, localized prostate cancer using active surveillance.
