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Recent developments in the methodology and application of MEEKC
Richie Ryan1, Eamon McEvoy, Sheila Donegan
1Waterford Institute of Technology, Waterford, Ireland. rjryan@wit.ie
Electrophoresis
|December 21, 2010
Summary
Microemulsion electrokinetic chromatography (MEEKC) offers advanced solute separation using microemulsions as electrolytes. This review covers MEEKC advancements from 2008-2010, including new applications and techniques.
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Microemulsions (MEs) are oil-in-water or water-in-oil nanodroplet systems stabilized by surfactants.
- MEEKC utilizes ME properties as background electrolytes for electrodriven separations.
- MEEKC enables the separation of diverse solute types.
Purpose of the Study:
- To review advances in Microemulsion Electrokinetic Chromatography (MEEKC) separations.
- To cover the period from June 2008 to June 2010.
- To provide a fundamental introduction to MEEKC and its applications.
Main Methods:
- Review of MEEKC literature from June 2008 - June 2010.
- Focus on techniques like online sample concentration and suppressed electroosmosis MEEKC.
- Inclusion of hyphenated techniques such as MEEKC-MS and MEEKC-ICP-MS.
Main Results:
- Detailed advances in MEEKC-based separations.
- Exploration of chiral separations and ME structure characterization.
- Compilation of recent MEEKC applications.
Conclusions:
- MEEKC continues to evolve with new techniques and applications.
- The review highlights significant progress in the field over a two-year period.
- MEEKC remains a versatile technique for complex separations.

