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Updated: Jun 5, 2026

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
Published on: August 12, 2018
[Psychiatric indications of deep brain stimulation]
Bruno Millet1, Marc Vérin, Dominique Drapier
1Pôle Hospitalo-Universitaire de Psychiatrie Adulte de, CH Guillaume Regnier, 108, avenue du Gal Leclerc, - BP 60324, 35703 Rennes cedex. bruno.millet@univ-rennes1.fr
Abstract:
Introduced at the end of the 1980s, high-frequency deep brain stimulation has shown its efficacy in several neurological disorders, including Parkinson's disease, dystonia and essential tremor, in which cortico-subcortical circuit dysfunction is strongly implicated. The existence of psychiatric symptoms in patients with these syndromes has led to the use of this technique in psychiatric disorders, and especially in severe refractory obsessive-compulsive disorders, even though the anatomical target is still controversial. Other potential indications include refractory chronic depression.

