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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

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Related Experiment Video

Updated: Jun 5, 2026

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

Ectopic thyroid of the lung. An additional case.

N Di Mari1, L Barbagli, V Mourmouras

  • 1Section of Anatomical Pathology, Department of Human Pathology and Oncology, University of Siena, Italy.

Pathologica
|December 22, 2010
PubMed
Summary

Thyroid ectopy is rare, typically found in the neck. This case study details an unusual autopsy finding of ectopic thyroid tissue discovered incidentally within the lung of an elderly male.

Area of Science:

  • Pathology
  • Endocrinology
  • Anatomical Abnormalities

Background:

  • Thyroid ectopy is a congenital condition where thyroid tissue is found outside its normal location.
  • Most commonly, ectopic thyroid tissue presents along the thyroglossal duct pathway in the cervical midline.
  • Other reported locations are rare, making each case significant for understanding developmental pathways.

Observation:

  • An incidental finding of ectopic thyroid tissue was made during the autopsy of a 77-year-old male.
  • The aberrant thyroid tissue was located within the lung parenchyma.
  • No clinical history suggestive of thyroid dysfunction or prior diagnosis was available for this individual.

Findings:

  • Histological examination confirmed the presence of normal thyroid follicular tissue within the lung.

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Last Updated: Jun 5, 2026

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
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Published on: November 10, 2014

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  • This represents an extremely rare and unusual anatomical location for ectopic thyroid tissue.
  • The finding was incidental and not associated with any apparent pathology in the lung.
  • Implications:

    • This case expands the known spectrum of locations for ectopic thyroid tissue.
    • It highlights the importance of thorough examination during autopsy, even in the absence of suspected pathology.
    • Further research into the embryological mechanisms behind such rare ectopic presentations may be warranted.