Jove
Visualize
Contact Us

Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Update S2k-Guideline Helicobacter pylori and gastroduodenal ulcer disease of the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS).

Zeitschrift fur Gastroenterologie·2024
Same author

Classification of acute appendicitis (CAA): treatment directed new classification based on imaging (ultrasound, computed tomography) and pathology.

International journal of colorectal disease·2021
Same author

Improving treatment of patients with inflammatory bowel diseases: a controlled trial of a multifaceted intervention in two German cities.

International journal of colorectal disease·2019
Same author

Guideline recommendations for treatment of patients with inflammatory bowel diseases are not implemented in clinical practice-results of a non-representative survey.

International journal of colorectal disease·2018
Same author

[S2k guideline Helicobacter pylori and gastroduodenal ulcer disease 2016 - Statement on stress ulcer prophylaxis and optimized therapy].

Zeitschrift fur Gastroenterologie·2017
Same author

[Not Available].

MMW Fortschritte der Medizin·2016
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 5, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Pulmonary abnormalities in inflammatory bowel disease.

Dietlind Schleiermacher1, Jörg C Hoffmann

  • 1Abteilung Innere Medizin I, St. Marienkrankenhaus, Ludwigshafen, Germany.

Journal of Crohn'S & Colitis
|December 22, 2010
PubMed
Summary
This summary is machine-generated.

Pulmonary disease is a rare extraintestinal manifestation of inflammatory bowel disease (IBD). Evaluation should prioritize drug-induced lung issues and infections before attributing lung problems to IBD itself.

Related Experiment Videos

Last Updated: Jun 5, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Area of Science:

  • Gastroenterology
  • Pulmonology
  • Pharmacology

Background:

  • Extraintestinal manifestations (EIMs) affect up to 50% of inflammatory bowel disease (IBD) patients.
  • Pulmonary disease is a less common, but significant, IBD-associated EIM.
  • Differential diagnosis is crucial for effective management.

Purpose of the Study:

  • To review the causes of pulmonary disease in IBD patients.
  • To emphasize the importance of considering drug-induced lung disease and infections.
  • To guide clinicians in the diagnostic approach.

Main Methods:

  • Literature review of pulmonary complications in IBD.
  • Analysis of drug-induced pulmonary toxicity.
  • Evaluation of opportunistic infections in immunosuppressed IBD patients.
  • Categorization of non-drug-related pulmonary disorders.

Main Results:

  • Drug-induced lung disease (sulfasalazine, mesalamine, methotrexate) is a frequent cause.
  • Opportunistic infections are increasingly recognized in immunosuppressed IBD patients.
  • A spectrum of airway and interstitial lung disorders can occur.

Conclusions:

  • Pulmonary disease in IBD requires a thorough evaluation.
  • Drug-induced lung disease and opportunistic infections must be ruled out.
  • Pulmonary conditions should only be considered IBD-related EIMs after other causes are excluded.