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Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Breathing abnormalities in children with breathlessness
1Paediatric Respiratory Physician, Princess Amalia Children's Clinic, Isala Klinieken, Zwolle, The Netherlands. e.p.de.groot@isala.nl
Insights
Dysfunctional breathing, including hyperventilation and vocal cord dysfunction, is common but lacks diagnostic standards. While reassurance helps, further research is needed to optimize treatment outcomes, especially for children.
Area of Science:
- Respiratory Medicine
- Pediatric Pulmonology
- Clinical Diagnostics
Background:
- Dysfunctional breathing (DB), hyperventilation, and vocal cord dysfunction are prevalent in pediatric and adult populations.
- Current diagnostic approaches rely on excluding organic diseases due to a lack of standardized criteria for DB.
- Existing therapies primarily involve patient education and reassurance, acknowledging DB as a potentially chronic condition.
Purpose of the Study:
- To review the current understanding of dysfunctional breathing, hyperventilation, and vocal cord dysfunction.
- To highlight the diagnostic challenges and therapeutic limitations in managing these conditions.
- To emphasize the need for further research, particularly in optimizing pediatric treatment strategies.
Main Methods:
- Literature review of studies on dysfunctional breathing, hyperventilation, and vocal cord dysfunction.
- Analysis of current diagnostic criteria and therapeutic interventions.
- Evaluation of evidence for treatment efficacy in adults and children.
Main Results:
- Dysfunctional breathing disorders are frequently observed but their prevalence remains undetermined.
- The absence of standardized diagnostic criteria complicates accurate diagnosis, often relying on the exclusion of organic pathologies.
- Physiotherapy and breathing retraining show promise in adult management, whereas evidence for pediatric interventions is limited.
Conclusions:
- Dysfunctional breathing is a significant clinical issue requiring better diagnostic tools and therapeutic approaches.
- Current management strategies are insufficient, particularly for pediatric patients.
- Further research is essential to develop evidence-based treatments and improve outcomes for children with dysfunctional breathing.
Abstract:
Dysfunctional breathing, hyperventilation and vocal cord dysfunction are frequently seen in children and adults. The prevalence is unknown. There are no standardized diagnostic criteria, and for now, effective exclusion of organic disease leaves the diagnosis of dysfunctional breathing. Therapy is mainly focussed on explanation of a benign condition and reassurance. Since dysfunctional breathing is a possible chronic condition, other therapies should be evaluated. In adults physiotherapy and breathing retraining appear beneficial. In childhood there is lack of evidence, and further research is necessary in order to optimise the outcome for children with dysfunctional breathing.
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