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Breath Collection from Children for Disease Biomarker Discovery

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Published on: February 14, 2019

Breathing abnormalities in children with breathlessness.

¹Paediatric Respiratory Physician, Princess Amalia Children's Clinic, Isala Klinieken, Zwolle, The Netherlands. e.p.de.groot@isala.nl

Paediatric Respiratory Reviews

|December 22, 2010

Summary

This summary is machine-generated.

Dysfunctional breathing, including hyperventilation and vocal cord dysfunction, is common but lacks diagnostic standards. While reassurance helps, further research is needed to optimize treatment outcomes, especially for children.

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Area of Science:

Respiratory Medicine
Pediatric Pulmonology
Clinical Diagnostics

Background:

Dysfunctional breathing (DB), hyperventilation, and vocal cord dysfunction are prevalent in pediatric and adult populations.
Current diagnostic approaches rely on excluding organic diseases due to a lack of standardized criteria for DB.
Existing therapies primarily involve patient education and reassurance, acknowledging DB as a potentially chronic condition.

Purpose of the Study:

To review the current understanding of dysfunctional breathing, hyperventilation, and vocal cord dysfunction.
To highlight the diagnostic challenges and therapeutic limitations in managing these conditions.
To emphasize the need for further research, particularly in optimizing pediatric treatment strategies.

Main Methods:

Literature review of studies on dysfunctional breathing, hyperventilation, and vocal cord dysfunction.
Analysis of current diagnostic criteria and therapeutic interventions.
Evaluation of evidence for treatment efficacy in adults and children.

Main Results:

Dysfunctional breathing disorders are frequently observed but their prevalence remains undetermined.
The absence of standardized diagnostic criteria complicates accurate diagnosis, often relying on the exclusion of organic pathologies.
Physiotherapy and breathing retraining show promise in adult management, whereas evidence for pediatric interventions is limited.

Conclusions:

Dysfunctional breathing is a significant clinical issue requiring better diagnostic tools and therapeutic approaches.
Current management strategies are insufficient, particularly for pediatric patients.
Further research is essential to develop evidence-based treatments and improve outcomes for children with dysfunctional breathing.