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Related Concept Videos

Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Histology of the Gastrointestinal (GI) Tract01:20

Histology of the Gastrointestinal (GI) Tract

The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
Histology of the Large Intestine01:26

Histology of the Large Intestine

The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
Histology of the Small Intestine01:27

Histology of the Small Intestine

The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Classification of Epithelial Tissues: Glandular Epithelium01:20

Classification of Epithelial Tissues: Glandular Epithelium

The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...

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Related Experiment Video

Updated: Jun 5, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
04:08

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions

Published on: April 28, 2026

[Incidental gastrointestinal subepithelial mass].

Sang Gyun Kim1

  • 1Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea. harley@snu.ac.kr

The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi
|December 22, 2010
PubMed
Summary

Incidental gastrointestinal subepithelial masses are increasingly found during cancer screening. This review covers diagnosing these tumors, focusing on differentiating benign growths from potentially malignant gastrointestinal stromal tumors.

Related Experiment Videos

Last Updated: Jun 5, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
04:08

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions

Published on: April 28, 2026

Area of Science:

  • Gastroenterology
  • Oncology
  • Diagnostic Imaging

Background:

  • The incidence of incidental gastrointestinal subepithelial masses is rising due to widespread cancer screening endoscopy.
  • While most subepithelial masses are small, asymptomatic, and benign, the potential for malignant gastrointestinal stromal tumors necessitates careful evaluation.

Purpose of the Study:

  • To present a comprehensive review of the differential diagnosis for incidentally discovered gastrointestinal subepithelial masses.
  • To outline effective treatment strategies for these lesions.

Main Methods:

  • Conventional endoscopy for initial assessment.
  • Endoscopic ultrasonography (EUS) for enhanced characterization of subepithelial masses.
  • EUS-guided biopsy for definitive histological diagnosis.

Main Results:

  • Conventional endoscopy alone has limitations in differentiating the nature of subepithelial masses.
  • Endoscopic ultrasonography significantly improves diagnostic accuracy.
  • EUS-guided biopsy provides a more definitive diagnosis, crucial for identifying malignant potential.

Conclusions:

  • Accurate diagnosis of gastrointestinal subepithelial masses is essential, particularly for ruling out gastrointestinal stromal tumors.
  • A combination of advanced endoscopic techniques, including EUS and biopsy, is recommended for optimal management.
  • This review provides a framework for the differential diagnosis and treatment of incidental gastrointestinal subepithelial masses.