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Updated: Jun 5, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Chronic Non-granulomatous ulcerative jejunoileitis assessed by wireless capsule endoscopy
Hyung Hun Kim1, You Sun Kim, Kyung Sun Ok
1Departments of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
A rare small bowel disease, chronic non-granulomatous jejunoileitis, was diagnosed in a 69-year-old man. Wireless capsule endoscopy aided diagnosis and surgical resection successfully treated his protein-losing enteropathy.
Area of Science:
- Gastroenterology
- Digestive Diseases
- Small Bowel Disorders
Background:
- Chronic non-granulomatous jejunoileitis is a rare condition causing malabsorption, pain, and diarrhea.
- Its etiology remains unknown, presenting diagnostic challenges.
Observation:
- A 69-year-old male presented with abdominal pain and lower extremity edema.
- A 99m-Tc albumin scan suggested protein-losing enteropathy; small bowel follow-through was unremarkable.
- Wireless capsule endoscopy identified small bowel ulcers and strictures.
Findings:
- Histologic examination revealed non-granulomatous ulcers and focal villous atrophy.
- The patient was diagnosed with chronic non-granulomatous ulcerative jejunoileitis after excluding other causes.
- Surgical segmentectomy resulted in symptom improvement and normalized serum albumin.
Implications:
- This case highlights the utility of wireless capsule endoscopy in diagnosing rare small bowel diseases.
- Successful surgical management offers a potential treatment strategy for this condition.
- Further research into the etiology of chronic non-granulomatous jejunoileitis is warranted.
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