[Indomethacin in the prevention of para-articular ossification following total hip endoprosthesis]

Indomethacin for prophylaxis of para-articular ossifications (PAO) after Total-Hip-Replacement We studied in a retrospective clinical trial the effect of indomethacin on the prevention of formation of heterotopic bone after total hip replacement. Compared were the grade lesions of ossification (described by Arcq) in the group of 63 patients that had received with the group of patients without indomethacin. Significantly fewer patients (p less than or equal to 0.001) who had received indomethacin had formation of heterotopic bone compared with the control group.