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The reactive serine residue of epidermolytic toxin A
1Department of Biochemistry, Trinity College, Dublin, Ireland.
The Biochemical Journal
|July 15, 1990
Abstract:
Comparison of amino acid sequence data suggested that there may be a functional relationship between the staphylococcal epidermolytic toxins and V8 proteinase. The hypothesis was tested by treating epidermolytic toxin with di-isopropyl phosphorofluoridate, which bound specifically at serine-195, the homologue of the active-site serine residue of V8 proteinase.