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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Related Experiment Video

Updated: Jun 5, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

[Liver transplantation].

Shinji Uemoto1

  • 1Department of Surgery, Division of Hepato-Pancreato-Biliary Surgery, Kyoto University Graduate School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 24, 2010
PubMed
Summary
This summary is machine-generated.

Living donor liver transplantation (LDLT) in Japan offers high survival rates for pediatric patients, with expanded indications for adults. Japan

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Orthotopic Liver Transplantation in Rats
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Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

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Related Experiment Videos

Last Updated: Jun 5, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

Orthotopic Liver Transplantation in Rats
18:25

Orthotopic Liver Transplantation in Rats

Published on: July 1, 2012

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

Area of Science:

  • Hepatology
  • Transplantation Surgery
  • Medical Policy

Context:

  • Living donor liver transplantation (LDLT) has been performed for pediatric patients since 1989 and expanded to adults, overcoming small-for-size graft challenges.
  • Annual LDLT cases in Japan approach 500, with pediatric patient survival rates exceeding 90%.
  • Deceased donor liver transplantation (DDLT) has seen limited application, with fewer than 10 cases annually since 1999.

Purpose:

  • To describe the unique landscape of liver transplantation in Japan, characterized by a high prevalence of LDLT.
  • To highlight the advancements and outcomes in LDLT, particularly for pediatric recipients.
  • To note the recent modification of Japan's organ transplantation law to align with international standards.

Summary:

  • Liver transplantation in Japan is predominantly LDLT (>98%), contrasting with the minimal DDLT (<2%).
  • Pediatric LDLT outcomes have significantly improved, achieving over 90% patient survival.
  • The indication for LDLT has broadened to include adult patients, addressing previous graft size limitations.

Impact:

  • The findings underscore Japan's specialized approach to liver transplantation, driven by LDLT.
  • Improved outcomes and expanded indications for LDLT offer viable solutions for liver disease patients.
  • The updated organ transplantation law facilitates a more standardized and potentially expanded donor pool.