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Updated: Jun 5, 2026
Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
Published on: February 14, 2022
[Heart and lung transplantation in children--current status and perspectives]
1Department of Pediatrics, Division of Pediatric Cardiology, Toho University, Medical Center, Omori Hospital.
Insights
Pediatric organ donation and transplantation offer significant benefits for children with severe heart and lung diseases. Despite stable transplant numbers, survival rates at 5 years are 50% for lung and 75% for heart transplants.
Area of Science:
- Pediatric Medicine
- Transplant Surgery
- Organ Donation
Context:
- Pediatric organ transplantation provides life-saving treatment for children with end-stage heart and lung diseases.
- Recent data show approximately 450 pediatric heart transplants (HT) and 90 lung transplants (LT) annually.
- The International Society for Heart and Lung Transplantation (ISHLT) registry tracks these procedures.
Purpose:
- To highlight the critical role and outcomes of pediatric organ transplantation.
- To underscore the importance of organ availability and access for pediatric patients.
- To inform pediatricians about the benefits and challenges in pediatric HT and LT.
Summary:
- Pediatric heart and lung transplantation offer substantial benefits to critically ill children.
- Survival rates at 5 years post-transplant are approximately 75% for HT and 50% for LT.
- Dilated cardiomyopathy and pulmonary arterial hypertension are leading indications for pediatric HT and LT, respectively.
Impact:
- Improved quality of life and survival for children with intractable heart and lung conditions.
- Emphasizes the need for increased organ availability and equitable access to transplantation.
- Reinforces the life-saving potential of organ donation in pediatric care.
Abstract:
In fact, pediatric organ donation and transplantation give a significant benefit to diseased children and their parents. During recent 3 years, the number of reported pediatric heart transplantation (HT) has remaining unchanged at -450/year, and the number of lung transplantation (LT) was reported around 90/year in the registry of ISHLT. The prognosis is not so different from that of adults, fifty % in LT and 75% in HT at 5 years. Dilated cardiomyopathy in HT and pulmonary arterial hypertension in LT are the most common diseases of indications. Important issues for all pediatricians include availability, and access to donor organ. The warm heart with gift of life or organ donation surely cure children suffered from intractable heart and lung diseases.
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