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Updated: Jun 5, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
[Effects of a specific health guidance program for prevention of diabetes]
Sanae Tomita1, Kazue Ninomiya, Hiroko Fukuhara
1Department of Nursing, Faculty of Health and Welfare Science, Okayama Prefectural University.
Purpose:
A follow-up survey was carried out to examine the effects of a health guidance program by comparing data before and after the intervention.
Methods:
The subjects comprised 20 potential diabetes patients aged between 40 and 64 years who were covered by health insurance and underwent a basic health check-up between August and September 2007. They were given detailed advice on health promotion for six months. We compared the results of a questionnaire survey, designed to examine their lifestyle habits and health awareness, and a blood test with changes over time. At the end of follow-up training, we conducted a semi-structured group interview to examine their lifestyles.
Results:
At the completion of the program, decreases in body weight, BMI, abdominal circumference, T. G., and HbAlc were marked (P < 0.05). However, the one-year follow-up survey could not be completed for the majority of the subjects and values for blood and other parameters showed no or little change from those measured prior to the start of the program. One year later, we interviewed the group, and the results were grouped into eleven categories.
Conclusion:
The six-month guidance program was effective at reducing BMI, HbA1c, and other relevant parameters. Within a year, however, return to close to the levels at the start of the program was noted. Although most subjects obtained support from their spouse, they did not change their dietary habits because it was difficult for them to seek cooperation from other family members. Thus, it is necessary to improve skills required for health advice.
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