Related Experiment Video
Updated: Jun 5, 2026

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
Published on: February 19, 2016
[Preparation and characterization of non-ionic surfactant vesicle of cantharidin]
Hui Li1, Qingying Fang, Hong Zhang
1Institute of Chinese Materia Medica, Chinese Acadamy of Chinese Medical Science, Beijing 100700, China.
Objective:
To study the preparation of cantharidin entrapped non-ionic surfactant vesicle (noisome)and evaluate its quality.
Method:
The niosome loaded with cantharidin was prepared using injection method by non-ionic surfactants as the carrier. An centrifugation separation method and HPLC analysis method of the cantharidin were established to detect the entrapment efficiency. The optimum preparation technology was established by a orthogonal experiment. The morphology, and particle size were studied to evaluate the preparation.
Result:
The average size of niosomes were (209. 8 +/- 0.5) nm. The entrapment efficiency of the CTD-NS was (27.5% +/- 2.0%) and Zeta potential was (41.5 +/- 0.65) mV.
Conclusion:
The preparation of cantharidin noisome by TweenA and SpanB is practicable and successful. These experiments can be the basement of developing targeting drug delivery system.
Related Concept Videos
Micelles
Surface Active Agents

