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Vaccinations

Vaccinations

Vaccines

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

Smallpox

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.

Vaccine Production

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

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Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

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[Vaccination: a programme for the whole life].

Pierre Olivier Lang¹, Jean-Pierre Michel

¹Département de réhabilitation et gériatrie, Hôpital des Trois-Chêne, HUG. pierre.o.lang@hcuge.ch

Revue Medicale Suisse

|December 24, 2010

Summary

This summary is machine-generated.

Vaccination significantly reduces infectious disease burden in older adults. Implementing a life-course vaccination program is crucial for preventing measles, pertussis, influenza, and other preventable diseases in Switzerland.

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Area of Science:

Gerontology and Infectious Disease Prevention
Public Health and Epidemiology
Vaccinology

Context:

Infectious diseases pose a significant health risk to the elderly population in Switzerland.
Vaccination strategies for older adults have historically been underemphasized.
Recent recommendations from EUGMS and IAGG-ER advocate for a dedicated adult vaccine schedule and life-course vaccination.

Purpose:

To highlight the impact of vaccines on reducing the incidence of specific infectious diseases in Switzerland.
To present the disease burden of vaccine-preventable infections in under-immunized elderly populations.
To advocate for the adoption of a life-course vaccination program to mitigate infectious disease impact.

Summary:

This article reviews the positive effects of vaccines against measles, pertussis, diphtheria, tetanus, influenza, and pneumococcal diseases.
It details the substantial morbidity and mortality caused by these diseases in unvaccinated or under-vaccinated older adults in Switzerland.
The analysis demonstrates that a life-course vaccination approach can substantially decrease the burden of these infectious diseases.

Impact:

Vaccination offers a proven method to reduce the incidence and severity of infectious diseases in older adults.
Adoption of a life-course vaccination program can lead to significant public health benefits and reduced healthcare costs.
Promoting adult immunization is essential for protecting vulnerable populations and improving overall health outcomes.