Highly water-soluble neutral BODIPY dyes with controllable fluorescence quantum yields
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Published on: October 9, 2012
Shilei Zhu1, Jingtuo Zhang, Giri Vegesna
1Department of Chemistry, Michigan Technological University, Houghton, Michigan 49931, USA.
Abstract:
A series of novel highly water-soluble neutral BODIPY dyes have been obtained by functionalization of BODIPY dyes with branched oligo(ethylene glycol)methyl ether groups at positions 8, 2 and 6 or 4 and 4'. Use of an ortho-substituent group of branched oligo(ethylene glycol)methyl ether on the meso-phenyl ring of BODIPY dyes and replacement of the fluorine atoms of BODIPY dyes at positions 4 and 4' with methyloxy or ethynyl subunits significantly enhance fluorescence quantum yields of BODIPY dyes.
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